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  • Writer's pictureRachel Davies

Exploring the Gut:Brain Axis



The human body is a complex network of interconnected systems, and one intriguing connection that has gained significant attention in the scientific community in recent years is the gut-brain axis. Ever felt 'butterflies in your tummy' when you are nervous, or gone with your 'gut instinct', this is the gut-brain axis in action. This bidirectional communication system between the gut and the brain plays a vital role in our overall well-being, influencing not only our physical health but also our mental health. Here I delve into the intricate relationship between gut health and mental health, as well as how mental health and stress can manifest as digestive symptoms.


The Gut-Brain Axis: A Dynamic Communication Highway


The gut-brain axis refers to the constant communication and feedback loop between the gastrointestinal tract (the gut) and the central nervous system (the brain). This axis is primarily mediated by the vagus nerve, a crucial nerve that connects these two vital systems. However, it also involves hormonal and immune signalling pathways too. So what that means is the emotional and cognitive parts of our brain, can impact our digestive functions, and vice versa. Incredible!






Gut Health and Mental Health:

  1. Neurotransmitters and Mood Regulation: The gut houses an extensive network of neurons known as the enteric nervous system (ENS), often referred to as the "second brain." This intricate web produces and releases various neurotransmitters, including serotonin, dopamine, and gamma-aminobutyric acid (GABA), which are key players in regulating mood and emotions. In fact, approximately 90% of serotonin, a neurotransmitter closely associated with happiness, is produced in the gut. An imbalance in these neurotransmitters can contribute to the development of mental health disorders such as depression and anxiety.

  2. Inflammation and the Immune Response: The gut plays a vital role in modulating the immune system. Imbalances in gut bacteria, a condition known as dysbiosis, can lead to chronic low-grade inflammation. This inflammation triggers an immune response that can impact brain function and mood. Research suggests that increased inflammation in the gut may contribute to the development of psychiatric conditions.

  3. The Microbiome: A Key Player: The gut is home to trillions of microorganisms collectively known as the gut microbiota. These microorganisms perform essential functions, such as aiding in digestion, synthesising vitamins, and training the immune system. They also play a critical role in the bidirectional communication with the brain. Alterations in the composition and diversity of the gut microbiota have been linked to mental health disorders, highlighting the significance of maintaining a healthy gut microbiome.



The Mind-Gut Connection: Stress and Digestive Symptoms

  1. The Impact of Stress: Stress can have a profound effect on our digestive system. When we experience stress, the brain releases stress hormones, such as cortisol and adrenaline, which can affect gut motility, increase intestinal permeability, and alter gut microbiota. This disruption in the gut can lead to various digestive symptoms, including abdominal pain, bloating, diarrhoea, and constipation.

  2. The Role of the Gut in our Stress Response: Interestingly, the gut also influences our response to stress. The gut microbiota communicates with the brain through the gut-brain axis, modulating the stress response and influencing the production of stress hormones. Imbalances in the gut microbiota can impair this communication, potentially exacerbating stress-related symptoms.

  3. Functional Gastrointestinal Disorders: Chronic stress and mental health conditions can contribute to the development of functional gastrointestinal disorders (FGIDs), such as irritable bowel syndrome (IBS). FGIDs are characterised by recurring digestive symptoms without apparent structural or biochemical abnormalities. The intricate relationship between stress, mental health, and gut function highlights the need for a holistic approach to managing these conditions.


The gut-brain axis serves as an amazing example of the interconnectedness of our body systems. Maintaining a healthy gut is not only crucial for digestive health but also for promoting optimal mental well-being. Nurturing a diverse gut microbiome, adopting stress-reduction techniques, and incorporating a balanced diet can positively impact both our gut and mental health.


If you feel like your niggling digestive issues are getting out of hand or your mental health is struggling, I offer a FREE 20 minute call to discuss how nutritional therapy can support you to optimise and elevate your wellbeing. You can book straight into my diary here.





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